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Cellular abundance of sodium phosphate cotransporter SLC20A1/PiT1 and phosphate uptake are controlled post-transcriptionally by ESCRT

Inorganic phosphate is essential for human life. The widely expressed mammalian sodium/phosphate cotransporter SLC20A1/PiT1 mediates phosphate uptake into most cell types; however, while SLC20A1 is required for development, and elevated SLC20A1 expression is associated with vascular calcification an...

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Detalles Bibliográficos
Autores principales: Zechner, Christoph, Henne, W. Mike, Sathe, Adwait A., Xing, Chao, Hernandez, Genaro, Sun, Shengyi, Cheong, Mi Cheong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123275/
https://www.ncbi.nlm.nih.gov/pubmed/35447110
http://dx.doi.org/10.1016/j.jbc.2022.101945