Evolution of Streptococcus pyogenes has maximized the efficiency of the Sortase A cleavage motif for cell wall transpeptidation

Trafficking of M-protein (Mprt) from the cytosol of Group A Streptococcus pyogenes (GAS) occurs via Sec translocase membrane channels that associate with Sortase A (SrtA), an enzyme that catalyzes cleavage of Mprt at the proximal C-terminal [-LPST(355∗)GEAA-] motif and subsequent transpeptidation of...

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Detalles Bibliográficos
Autores principales: Readnour, Bradley M., Ayinuola, Yetunde A., Russo, Brady T., Liang, Zhong, Lee, Shaun W., Ploplis, Victoria A., Fischetti, Vincent A., Castellino, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123276/
https://www.ncbi.nlm.nih.gov/pubmed/35430253
http://dx.doi.org/10.1016/j.jbc.2022.101940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123276/
https://www.ncbi.nlm.nih.gov/pubmed/35430253
http://dx.doi.org/10.1016/j.jbc.2022.101940

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