Cargando…

Association of FOXO3 polymorphism (rs3800231) and clinical subphenotypes of beta thalassemic individuals

INTRODUCTION: Studies have shown that the loss of the FOXO3 transcriptional function is involved in the pathophysiology of some chronic erythroid disorders, including beta-thalassemia (β-thal). Therefore, the single nucleotide polymorphism (SNP) rs3800231 (35-2764A > G) could contribute to altera...

Descripción completa

Detalles Bibliográficos
Autores principales: Torres, Flaviene F., Bernardo, Victoria S., Silva, Danilo G.H., Okumura, Jéssika V., Bonini-Domingos, Claudia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123579/
https://www.ncbi.nlm.nih.gov/pubmed/33309469
http://dx.doi.org/10.1016/j.htct.2020.09.147