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Association of FOXO3 polymorphism (rs3800231) and clinical subphenotypes of beta thalassemic individuals
INTRODUCTION: Studies have shown that the loss of the FOXO3 transcriptional function is involved in the pathophysiology of some chronic erythroid disorders, including beta-thalassemia (β-thal). Therefore, the single nucleotide polymorphism (SNP) rs3800231 (35-2764A > G) could contribute to altera...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Hematologia e Hemoterapia
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123579/ https://www.ncbi.nlm.nih.gov/pubmed/33309469 http://dx.doi.org/10.1016/j.htct.2020.09.147 |