Glucagon-Like Peptide-2 Stimulates S-Phase Entry of Intestinal Lgr5+ Stem Cells

BACKGROUND & AIMS: Leucine-rich repeat-containing G-protein–coupled receptor-5 (Lgr5)+/olfactomedin-4 (Olfm4)+ intestinal stem cells (ISCs) in the crypt base are crucial for homeostatic maintenance of the epithelium. The gut hormone, glucagon-like peptide-2(1–33) (GLP-2), stimulates intestinal p...

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Detalles Bibliográficos
Autores principales: Chen, Maegan E., Naeini, Setareh Malekian, Srikrishnaraj, Arjuna, Drucker, Daniel J., Fesler, Zivit, Brubaker, Patricia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123588/
https://www.ncbi.nlm.nih.gov/pubmed/35218981
http://dx.doi.org/10.1016/j.jcmgh.2022.02.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123588/
https://www.ncbi.nlm.nih.gov/pubmed/35218981
http://dx.doi.org/10.1016/j.jcmgh.2022.02.011

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