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Protocol of a randomized, double-blind, placebo-controlled study of the effect of probiotics on the gut microbiome of patients with gastro-oesophageal reflux disease treated with rabeprazole

BACKGROUND: For patients with gastro-oesophageal reflux symptoms, the preferred treatment is proton pump inhibitor (PPI) administration for approximately 8 weeks. However, long-term use of PPIs can cause gut microbiome (GM) disturbances. This study is designed to evaluate the effect of probiotics co...

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Detalles Bibliográficos
Autores principales: Liu, Wenjun, Xie, Yong, Li, Yingmeng, Zheng, Longjin, Xiao, Qiuping, Zhou, Xu, Li, Qiong, Yang, Ni, Zuo, Kexuan, Xu, Tielong, Lu, Nong-Hua, Zhang, Heping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123715/
https://www.ncbi.nlm.nih.gov/pubmed/35596146
http://dx.doi.org/10.1186/s12876-022-02320-y