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Discovery of honokiol thioethers containing 1,3,4-oxadiazole moieties as potential α-glucosidase and SARS-CoV-2 entry inhibitors

Honokiol, isolated from a traditional Chinese medicine (TCM) Magnolia officinalis, is a biphenolic compound with several biological activities. To improve and broaden its biological activity, herein, two series of honokiol thioethers bearing 1,3,4-oxadiazole moieties were prepared and assessed for t...

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Detalles Bibliográficos
Autores principales: Xu, Ting, Meng, Jie-Ru, Cheng, Wanqing, Liu, Jia-Zheng, Chu, Junyan, Zhang, Qian, Ma, Nannan, Bai, Li-Ping, Guo, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123836/
https://www.ncbi.nlm.nih.gov/pubmed/35617790
http://dx.doi.org/10.1016/j.bmc.2022.116838