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The Effects of a Novel Curcumin Derivative Loaded Long-Circulating Solid Lipid Nanoparticle on the MHCC-97H Liver Cancer Cells and Pharmacokinetic Behavior

PURPOSE: The objective of this study was to develop long-circulating solid lipid nanoparticles (LSLN) containing a novel curcumin (CU) derivative (CU1), to improve CU1ʹs pharmacokinetic behavior and its anti-cancer effects in MHCC-97H liver cancer cells. METHODS: LSLN loaded with CU1 (CU1-LSLN) was...

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Detalles Bibliográficos
Autores principales: Wei, Yumeng, Li, Ke, Zhao, Wenmei, He, Yingmeng, Shen, Hongping, Yuan, Jiyuan, Pi, Chao, Zhang, Xiaomei, Zeng, Mingtang, Fu, Shaozhi, Song, Xinjie, Lee, Robert J, Zhao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9123937/
https://www.ncbi.nlm.nih.gov/pubmed/35607705
http://dx.doi.org/10.2147/IJN.S363237