6,7-Dimethoxycoumarin Influences the Erythroid Differentiation of Human Chronic Myelogenous Leukemia K562 Cells through Regulating FOXO3/p27 Signal Pathway

OBJECTIVE: To study the pharmacological activity and the mechanism of action of natural compounds derived from 6,7-dimethoxycoumarin on the differentiation of human chronic myeloid leukemia K562 cells. METHODS: We use MTT assay (Sigma-Aldrich, USA) to detect cell viability; use flow cytometry to ana...

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Detalles Bibliográficos
Autores principales: Zheng, Li, Wu, Yu, Wang, Fu, Shi, Hui, Xu, Bo, Yang, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124080/
https://www.ncbi.nlm.nih.gov/pubmed/35607323
http://dx.doi.org/10.1155/2022/1138851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124080/
https://www.ncbi.nlm.nih.gov/pubmed/35607323
http://dx.doi.org/10.1155/2022/1138851

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