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Sex differences in telomere length, lifespan, and embryonic dyskerin levels

Telomerase levels in most human cells are insufficient to prevent loss of telomeric DNA with each replication cycle. The resulting “Hayflick” limit may have allowed lifespan to increase by suppressing the development of tumors early in life be it at the expense of compromised cellular responses late...

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Detalles Bibliográficos
Autor principal: Lansdorp, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124296/
https://www.ncbi.nlm.nih.gov/pubmed/35441417
http://dx.doi.org/10.1111/acel.13614