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Sex differences in telomere length, lifespan, and embryonic dyskerin levels
Telomerase levels in most human cells are insufficient to prevent loss of telomeric DNA with each replication cycle. The resulting “Hayflick” limit may have allowed lifespan to increase by suppressing the development of tumors early in life be it at the expense of compromised cellular responses late...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley and Sons Inc.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124296/ https://www.ncbi.nlm.nih.gov/pubmed/35441417 http://dx.doi.org/10.1111/acel.13614 |