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S‐adenosyl‐L‐homocysteine extends lifespan through methionine restriction effects
Methionine restriction (MetR) can extend lifespan and delay the onset of aging‐associated pathologies in most model organisms. Previously, we showed that supplementation with the metabolite S‐adenosyl‐L‐homocysteine (SAH) extends lifespan and activates the energy sensor AMP‐activated protein kinase...
Autores principales: | Ogawa, Takafumi, Masumura, Koji, Kohara, Yuki, Kanai, Muneyoshi, Soga, Tomoyoshi, Ohya, Yoshikazu, Blackwell, T. Keith, Mizunuma, Masaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124299/ https://www.ncbi.nlm.nih.gov/pubmed/35388610 http://dx.doi.org/10.1111/acel.13604 |
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