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Challenges of proving a causal role of somatic mutations in the aging process
Aging is accompanied by the progressive accumulation of permanent changes to the genomic sequence, termed somatic mutations. Small mutations, including single‐base substitutions and insertions/deletions, are key determinants of the malignant transformations leading to cancer, but their role as initi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124308/ https://www.ncbi.nlm.nih.gov/pubmed/35435316 http://dx.doi.org/10.1111/acel.13613 |