A modeling‐based proposal for safe and efficacious reintroduction of bedaquiline after dose interruption: A population pharmacokinetics study

Bedaquiline (BDQ) is recommended for treatment of multidrug‐resistant tuberculosis (MDR‐TB) for the majority of patients. Given its long terminal half‐life and safety concerns, such as QTc‐prolongation, re‐introducing BDQ after multiple dose interruption is not intuitive and there are currently no e...

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Detalles Bibliográficos
Autores principales: Keutzer, Lina, Akhondipour Salehabad, Yasamin, Davies Forsman, Lina, Simonsson, Ulrika S. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124352/
https://www.ncbi.nlm.nih.gov/pubmed/35102712
http://dx.doi.org/10.1002/psp4.12768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124352/
https://www.ncbi.nlm.nih.gov/pubmed/35102712
http://dx.doi.org/10.1002/psp4.12768

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