Cargando…
A modeling‐based proposal for safe and efficacious reintroduction of bedaquiline after dose interruption: A population pharmacokinetics study
Bedaquiline (BDQ) is recommended for treatment of multidrug‐resistant tuberculosis (MDR‐TB) for the majority of patients. Given its long terminal half‐life and safety concerns, such as QTc‐prolongation, re‐introducing BDQ after multiple dose interruption is not intuitive and there are currently no e...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124352/ https://www.ncbi.nlm.nih.gov/pubmed/35102712 http://dx.doi.org/10.1002/psp4.12768 |