Proarrhythmic risk assessment of drugs by dV (m) /dt shapes using the convolutional neural network

Comprehensive in vitro Proarrhythmia Assay (CiPA) projects for assessing proarrhythmic drugs suggested a logistic regression model using qNet as the Torsades de Pointes (TdP) risk assessment biomarker, obtained from in silico simulation. However, using a single in silico feature, such as qNet, canno...

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Detalles Bibliográficos
Autores principales: Jeong, Da Un, Yoo, Yedam, Marcellinus, Aroli, Kim, Ki‐Suk, Lim, Ki Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124356/
https://www.ncbi.nlm.nih.gov/pubmed/35579100
http://dx.doi.org/10.1002/psp4.12803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124356/
https://www.ncbi.nlm.nih.gov/pubmed/35579100
http://dx.doi.org/10.1002/psp4.12803

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