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Proarrhythmic risk assessment of drugs by dV (m) /dt shapes using the convolutional neural network

Comprehensive in vitro Proarrhythmia Assay (CiPA) projects for assessing proarrhythmic drugs suggested a logistic regression model using qNet as the Torsades de Pointes (TdP) risk assessment biomarker, obtained from in silico simulation. However, using a single in silico feature, such as qNet, canno...

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Detalles Bibliográficos
Autores principales:	Jeong, Da Un, Yoo, Yedam, Marcellinus, Aroli, Kim, Ki‐Suk, Lim, Ki Moo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124356/ https://www.ncbi.nlm.nih.gov/pubmed/35579100 http://dx.doi.org/10.1002/psp4.12803

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