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Progress in understanding the mechanisms of resistance to BCL-2 inhibitors
Venetoclax is a new type of BH3 mimetic compound that can target the binding site in the BCL-2 protein and induce apoptosis in cancer cells by stimulating the mitochondrial apoptotic pathway. Venetoclax is especially used to treat haematological malignancies. However, with the recent expansion in th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124382/ https://www.ncbi.nlm.nih.gov/pubmed/35598030 http://dx.doi.org/10.1186/s40164-022-00283-0 |