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Inhibition of MAT2A-Related Methionine Metabolism Enhances The Efficacy of Cisplatin on Cisplatin-Resistant Cells in Lung Cancer

OBJECTIVE: Tumor drug resistance is a vital obstacle to chemotherapy in lung cancer. Methionine adenosyltransferase 2A has been considered as a potential target for lung cancer treatment because targeting it can disrupt the tumorigenicity of lung tumor-initiating cells. In this study, we primarily o...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaoya, Wang, Lude, Lin, Haiping, Wang, Jing, Fu, Jianfei, Zhu, Dan, Xu, Wenxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124450/
https://www.ncbi.nlm.nih.gov/pubmed/35674024
http://dx.doi.org/10.22074/cellj.2022.7907