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Crocin protects the renal tubular epithelial cells against high glucose-induced injury and oxidative stress via regulation of the SIRT1/Nrf2 pathway

OBJECTIVE(S): Renal tubular damage is critical pathological feathers of diabetic nephropathy (DN). This study aimed to explore the protective activity and related mechanisms of crocin in renal epithelial cell injury induced by high glucose. MATERIALS AND METHODS: Renal tubular epithelial HK-2 cells...

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Detalles Bibliográficos
Autores principales: Zhang, Jichen, Zhao, Xuemei, Zhu, Hongling, Wang, Jingnan, Ma, Junhua, Gu, Mingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124533/
https://www.ncbi.nlm.nih.gov/pubmed/35655597
http://dx.doi.org/10.22038/IJBMS.2022.51597.11708