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Crocin protects the renal tubular epithelial cells against high glucose-induced injury and oxidative stress via regulation of the SIRT1/Nrf2 pathway
OBJECTIVE(S): Renal tubular damage is critical pathological feathers of diabetic nephropathy (DN). This study aimed to explore the protective activity and related mechanisms of crocin in renal epithelial cell injury induced by high glucose. MATERIALS AND METHODS: Renal tubular epithelial HK-2 cells...
Autores principales: | Zhang, Jichen, Zhao, Xuemei, Zhu, Hongling, Wang, Jingnan, Ma, Junhua, Gu, Mingjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124533/ https://www.ncbi.nlm.nih.gov/pubmed/35655597 http://dx.doi.org/10.22038/IJBMS.2022.51597.11708 |
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