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Crocin ameliorates MicroRNAs-associated ER stress in type 2 diabetes induced by methylglyoxal

OBJECTIVE(S): Methylglyoxal (MG) provokes endoplasmic reticulum (ER) stress in β-cells and triggers pancreatic β-cell dysfunction. Crocin has anti-diabetic properties. The present study investigated whether crocin prevented pancreas damages induced by MG. MATERIALS AND METHODS: Diabetes was induced...

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Detalles Bibliográficos
Autores principales: Radmehr, Vahid, Ahangarpour, Akram, Mard, Seyyed Ali, Khorsandi, Layasadat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124542/
https://www.ncbi.nlm.nih.gov/pubmed/35655590
http://dx.doi.org/10.22038/IJBMS.2022.60493.13407