Natural killer cells act as an extrinsic barrier for in vivo reprogramming

The ectopic expression of the transcription factors OCT4, SOX2, KLF4 and MYC (OSKM) enables reprogramming of differentiated cells into pluripotent embryonic stem cells. Methods based on partial and reversible in vivo reprogramming are a promising strategy for tissue regeneration and rejuvenation. Ho...

Descripción completa

Detalles Bibliográficos
Autores principales: Melendez, Elena, Chondronasiou, Dafni, Mosteiro, Lluc, Martínez de Villarreal, Jaime, Fernández-Alfara, Marcos, Lynch, Cian J., Grimm, Dirk, Real, Francisco X., Alcamí, José, Climent, Núria, Pietrocola, Federico, Serrano, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124575/
https://www.ncbi.nlm.nih.gov/pubmed/35420133
http://dx.doi.org/10.1242/dev.200361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124575/
https://www.ncbi.nlm.nih.gov/pubmed/35420133
http://dx.doi.org/10.1242/dev.200361

Ejemplares similares