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Overcoming radio-resistance in esophageal squamous cell carcinoma via hypermethylation of PIK3C3 promoter region mediated by KDM5B loss

Many patients with esophageal squamous cell carcinoma (ESCC) are inoperable because of old age or the advanced stage of the disease; thus radio- and chemotherapy are believed as the standard treatments for these patients. However, due to the radio-resistance of tumor cells that may develop during ra...

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Detalles Bibliográficos
Autores principales: Wang, Xiaobo, Gu, Min, Ju, Yongjian, Zhou, Juying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124615/
https://www.ncbi.nlm.nih.gov/pubmed/35333349
http://dx.doi.org/10.1093/jrr/rrac004