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Poly-γ-glutamic acid/Alum adjuvanted pH1N1 vaccine-immunized aged mice exhibit a significant increase in vaccine efficacy with a decrease in age-associated CD8(+) T cell proportion in splenocytes

BACKGROUND: Highly contagious respiratory diseases caused by viral infections are a constantly emerging threat, particularly the elderly with the higher risk of developing serious complications. Vaccines are the best strategy for protection against influenza-related diseases. However, the elderly ha...

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Detalles Bibliográficos
Autores principales: Yang, Jihyun, Kim, Jaemoo, Kwak, Chaewon, Poo, Haryoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124744/
https://www.ncbi.nlm.nih.gov/pubmed/35606855
http://dx.doi.org/10.1186/s12979-022-00282-z