Vincristine Promotes Transdifferentiation of Fibroblasts Into Myofibroblasts via P38 and ERK Signal Pathways

Background: Vincristine (VCR) is used in the clinic as an anti-tumor drug. VCR can cause pulmonary fibrosis (PF), leading to respiratory failure. The transformation of fibroblasts into myofibroblasts may play a key role in PF. The present study attempted to reveal the molecular mechanism of VCR-indu...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Hui, Yang, Jingwen, Tu, Mengyun, Weng, Jie, Xie, Mengying, Zhou, Zhiliang, Zhou, Peisen, Wang, Liang, Chen, Chan, Wang, Zhiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124770/
https://www.ncbi.nlm.nih.gov/pubmed/35614948
http://dx.doi.org/10.3389/fphar.2022.901000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124770/
https://www.ncbi.nlm.nih.gov/pubmed/35614948
http://dx.doi.org/10.3389/fphar.2022.901000

Ejemplares similares