Mitochondria-Targeted Mesoporous Organic Silica Nanoplatforms for Overcoming Cisplatin Resistance by Disturbing Mitochondrial Redox Homeostasis

Cisplatin (also known as DDP) resistance is one of the biggest challenges in the treatment of ovarian cancer. Recent studies have found that mitochondrion, as a potential target of DDP, participates in drug-related apoptosis and resistance. Overexpressed glutathione (GSH) in resistant cells is invol...

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Detalles Bibliográficos
Autores principales: Lv, Bin, Ma, Jingru, Wang, Yumeng, Qu, Xinyu, Qiu, Junjun, Hua, Keqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124779/
https://www.ncbi.nlm.nih.gov/pubmed/35615309
http://dx.doi.org/10.3389/fchem.2022.875818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124779/
https://www.ncbi.nlm.nih.gov/pubmed/35615309
http://dx.doi.org/10.3389/fchem.2022.875818

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