Cargando…

Src Activation Aggravates Podocyte Injury in Diabetic Nephropathy via Suppression of FUNDC1-Mediated Mitophagy

Background and purpose: Mitophagy plays a significant role in the progression of diabetic nephropathy (DN), although the regulatory mechanisms remain unclear. Recently, accumulating evidence demonstrated that impaired mitochondrial function and mitophagy are involved in DN. Here, we are aimed to exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Ting, Wang, Han-yu, Chen, Yang, Chen, Xiao, Wu, Zi-ling, Hu, Qin-yu, Sun, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124787/
https://www.ncbi.nlm.nih.gov/pubmed/35614934
http://dx.doi.org/10.3389/fphar.2022.897046