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HIV-1 gp120 Impairs Spatial Memory Through Cyclic AMP Response Element-Binding Protein
HIV-associated neurocognitive disorders (HAND) remain an unsolved problem that persists despite using antiretroviral therapy. We have obtained data showing that HIV-gp120 protein contributes to neurodegeneration through metabolic reprogramming. This led to decreased ATP levels, lower mitochondrial D...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124804/ https://www.ncbi.nlm.nih.gov/pubmed/35615594 http://dx.doi.org/10.3389/fnagi.2022.811481 |