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HIV-1 gp120 Impairs Spatial Memory Through Cyclic AMP Response Element-Binding Protein

HIV-associated neurocognitive disorders (HAND) remain an unsolved problem that persists despite using antiretroviral therapy. We have obtained data showing that HIV-gp120 protein contributes to neurodegeneration through metabolic reprogramming. This led to decreased ATP levels, lower mitochondrial D...

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Detalles Bibliográficos
Autores principales: Shrestha, Jenny, Santerre, Maryline, Allen, Charles N. S., Arjona, Sterling P., Merali, Carmen, Mukerjee, Ruma, Chitrala, Kumaraswamy Naidu, Park, Jin, Bagashev, Asen, Bui, Viet, Eugenin, Eliseo A., Merali, Salim, Kaul, Marcus, Chin, Jeannie, Sawaya, Bassel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124804/
https://www.ncbi.nlm.nih.gov/pubmed/35615594
http://dx.doi.org/10.3389/fnagi.2022.811481