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HIV-1 gp120 Impairs Spatial Memory Through Cyclic AMP Response Element-Binding Protein
HIV-associated neurocognitive disorders (HAND) remain an unsolved problem that persists despite using antiretroviral therapy. We have obtained data showing that HIV-gp120 protein contributes to neurodegeneration through metabolic reprogramming. This led to decreased ATP levels, lower mitochondrial D...
Autores principales: | Shrestha, Jenny, Santerre, Maryline, Allen, Charles N. S., Arjona, Sterling P., Merali, Carmen, Mukerjee, Ruma, Chitrala, Kumaraswamy Naidu, Park, Jin, Bagashev, Asen, Bui, Viet, Eugenin, Eliseo A., Merali, Salim, Kaul, Marcus, Chin, Jeannie, Sawaya, Bassel E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124804/ https://www.ncbi.nlm.nih.gov/pubmed/35615594 http://dx.doi.org/10.3389/fnagi.2022.811481 |
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