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Influence of SARS-CoV-2 inactivation by different chemical reagents on the humoral response evaluated in a murine model

Viral inactivation for antibody induction purposes, among other applications, should ensure biosafety, completely avoiding the risk of infectivity, and preserving viral immunogenicity. β-propiolactone (BPL) is one of the most used reagents for viral inactivation, despite its high toxicity and recent...

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Detalles Bibliográficos
Autores principales: de Castro Barbosa, Emerson, de Souza Andrade, Adriana, Duarte, Myrian Morato, Faria, Gilson, de Melo Iani, Felipe Campos, Ataide, Ana Caroline Zampiroli, Cunha, Lucas Maciel, Duarte, Clara Guerra, Fialho, Sílvia Ligorio, Caldas, Sérgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125173/
https://www.ncbi.nlm.nih.gov/pubmed/35644072
http://dx.doi.org/10.1016/j.molimm.2022.05.012