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Clinical and prognostic significance of expression of phosphoglycerate mutase family member 5 and Parkin in advanced colorectal cancer

BACKGROUND: Drugs targeting mitochondria can induce mitophagy and restrain proliferation in colorectal cancer (CRC) cells. Phosphoglycerate mutase family member 5 (PGAM5) activates serine/threonine PTEN-induced putative kinase 1/Parkin pathway-mediated mitophagy. However, there are few studies on th...

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Detalles Bibliográficos
Autores principales: Wu, Can, Feng, Ming-Liang, Jiao, Tai-Wei, Sun, Ming-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125282/
https://www.ncbi.nlm.nih.gov/pubmed/35663086
http://dx.doi.org/10.12998/wjcc.v10.i14.4368