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Lymphocytes in tumor-draining lymph nodes co-cultured with autologous tumor cells for adoptive cell therapy

BACKGROUND: Tumor-draining lymph nodes (TDLNs) are primary sites, where anti-tumor lymphocytes are primed to tumor-specific antigens and play pivotal roles in immune responses against tumors. Although adoptive cell therapy (ACT) using lymphocytes isolated from TDLNs were reported, characterization o...

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Detalles Bibliográficos
Autores principales: Okamura, Kazumi, Nagayama, Satoshi, Tate, Tomohiro, Chan, Hiu Ting, Kiyotani, Kazuma, Nakamura, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125345/
https://www.ncbi.nlm.nih.gov/pubmed/35606862
http://dx.doi.org/10.1186/s12967-022-03444-1