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How to use Donath-Landsteiner test to diagnose paroxysmal cold haemoglobinuria (PCH)

Paroxysmal cold haemoglobinuria (PCH) accounts for around a third of cases of autoimmune haemolytic anaemia in children. PCH is caused by an autoantibody that fixes complement to red cells at low temperatures and dissociates at warmer temperatures (a biphasic haemolysin), triggering complement-media...

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Detalles Bibliográficos
Autores principales: Williams, Jennifer Delun, Jayaprakash, Ram K, Kithany, Heena, Tighe, Mark Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125376/
https://www.ncbi.nlm.nih.gov/pubmed/34433582
http://dx.doi.org/10.1136/archdischild-2020-319568