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How to use Donath-Landsteiner test to diagnose paroxysmal cold haemoglobinuria (PCH)
Paroxysmal cold haemoglobinuria (PCH) accounts for around a third of cases of autoimmune haemolytic anaemia in children. PCH is caused by an autoantibody that fixes complement to red cells at low temperatures and dissociates at warmer temperatures (a biphasic haemolysin), triggering complement-media...
Autores principales: | Williams, Jennifer Delun, Jayaprakash, Ram K, Kithany, Heena, Tighe, Mark Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125376/ https://www.ncbi.nlm.nih.gov/pubmed/34433582 http://dx.doi.org/10.1136/archdischild-2020-319568 |
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