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Contribution of Mitochondria to Insulin Secretion by Various Secretagogues

SIGNIFICANCE: Mitochondria determine glucose-stimulated insulin secretion (GSIS) in pancreatic β-cells by elevating ATP synthesis. As the metabolic and redox hub, mitochondria provide numerous links to the plasma membrane channels, insulin granule vesicles (IGVs), cell redox, NADH, NADPH, and Ca(2+)...

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Detalles Bibliográficos
Autores principales: Ježek, Petr, Holendová, Blanka, Jabůrek, Martin, Dlasková, Andrea, Plecitá-Hlavatá, Lydie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125579/
https://www.ncbi.nlm.nih.gov/pubmed/34180254
http://dx.doi.org/10.1089/ars.2021.0113