Activin-A impairs CD8 T cell-mediated immunity and immune checkpoint therapy response in melanoma

BACKGROUND: Activin-A, a transforming growth factor β family member, is secreted by many cancer types and is often associated with poor disease prognosis. Previous studies have shown that Activin-A expression can promote cancer progression and reduce the intratumoral frequency of cytotoxic T cells....

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Detalles Bibliográficos
Autores principales: Pinjusic, Katarina, Dubey, Olivier Andreas, Egorova, Olga, Nassiri, Sina, Meylan, Etienne, Faget, Julien, Constam, Daniel Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125758/
https://www.ncbi.nlm.nih.gov/pubmed/35580932
http://dx.doi.org/10.1136/jitc-2022-004533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125758/
https://www.ncbi.nlm.nih.gov/pubmed/35580932
http://dx.doi.org/10.1136/jitc-2022-004533

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