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Bufalin stimulates antitumor immune response by driving tumor-infiltrating macrophage toward M1 phenotype in hepatocellular carcinoma

BACKGROUND: Immunotherapy for hepatocellular carcinoma (HCC) exhibits limited clinical efficacy due to immunosuppressive tumor microenvironment (TME). Tumor-infiltrating macrophages (TIMs) account for the major component in the TME, and the dominance of M2 phenotype over M1 phenotype in the TIMs pla...

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Detalles Bibliográficos
Autores principales: Yu, Zhuo, Li, Yuyao, Li, Yue, Zhang, Jinghao, Li, Man, Ji, Longshan, Tang, Yifei, Zheng, Yanxi, Sheng, Jianguo, Han, Qiucheng, Li, Fu, Guo, Jianfeng, Wang, Lingtai, Sun, Xuehua, Gao, Yueqiu, Feng, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125767/
https://www.ncbi.nlm.nih.gov/pubmed/35618286
http://dx.doi.org/10.1136/jitc-2021-004297