Brain-targeted heptapeptide-loaded exosomes attenuated ischemia–reperfusion injury by promoting the transfer of healthy mitochondria from astrocytes to neurons

BACKGROUND: The exchange of mitochondria reportedly plays an important role in cell–cell communication in the central nervous system (CNS). The transfer of fragmented and dysfunctional astrocytic mitochondria into neurons and subsequent mitochondrial fusion often cause serious neuronal damage and ce...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Su, Chang, Qi, Yao, Liang, Jia, Zhao, Liang, Shi, Yijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125840/
https://www.ncbi.nlm.nih.gov/pubmed/35606779
http://dx.doi.org/10.1186/s12951-022-01425-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125840/
https://www.ncbi.nlm.nih.gov/pubmed/35606779
http://dx.doi.org/10.1186/s12951-022-01425-6

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