Cargando…

Brain-targeted heptapeptide-loaded exosomes attenuated ischemia–reperfusion injury by promoting the transfer of healthy mitochondria from astrocytes to neurons

BACKGROUND: The exchange of mitochondria reportedly plays an important role in cell–cell communication in the central nervous system (CNS). The transfer of fragmented and dysfunctional astrocytic mitochondria into neurons and subsequent mitochondrial fusion often cause serious neuronal damage and ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Wei, Su, Chang, Qi, Yao, Liang, Jia, Zhao, Liang, Shi, Yijie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125840/ https://www.ncbi.nlm.nih.gov/pubmed/35606779 http://dx.doi.org/10.1186/s12951-022-01425-6

Ejemplares similares

Surface-modified engineered exosomes attenuated cerebral ischemia/reperfusion injury by targeting the delivery of quercetin towards impaired neurons
por: Guo, Lin, et al.
Publicado: (2021)

Transfer of mitochondria from astrocytes to neurons after stroke
por: Hayakawa, Kazuhide, et al.
Publicado: (2016)

Pterostilbene Attenuates Astrocytic Inflammation and Neuronal Oxidative Injury After Ischemia-Reperfusion by Inhibiting NF-κB Phosphorylation
por: Liu, Haixiao, et al.
Publicado: (2019)

Brain Microvascular Endothelial Cell-Derived Exosomes Protect Neurons from Ischemia–Reperfusion Injury in Mice
por: Sun, Jin, et al.
Publicado: (2022)

Ischemic Postconditioning Protects Neuronal Death Caused by Cerebral Ischemia and Reperfusion via Attenuating Protein Aggregation
por: Liang, Jianmin, et al.
Publicado: (2012)

Ginsenoside Rb1 inhibits astrocyte activation and promotes transfer of astrocytic mitochondria to neurons against ischemic stroke
por: Ni, Xue-Chun, et al.
Publicado: (2022)

Tetrandrine attenuates ischemia/reperfusion-induced neuronal damage in the subacute phase
por: Wang, Yu, et al.
Publicado: (2021)

Gap Junctional Coupling Between Retinal Astrocytes Exacerbates Neuronal Damage in Ischemia-Reperfusion Injury
por: Toychiev, Abduqodir H., et al.
Publicado: (2021)

Prostacyclin Analogue–Loaded Nanoparticles Attenuate Myocardial Ischemia/Reperfusion Injury in Rats
por: Yajima, Shin, et al.
Publicado: (2019)

Atomistic fibrillar architectures of polar prion-inspired heptapeptides
por: Peccati, Francesca, et al.
Publicado: (2020)

The Role of Mitochondria in the Mechanisms of Cardiac Ischemia-Reperfusion Injury
por: Kuznetsov, Andrey V., et al.
Publicado: (2019)

Screening of an annexin‐A2‐targeted heptapeptide for pancreatic adenocarcinoma localization
por: Ma, Heyao, et al.
Publicado: (2022)

Perioperative Dexmedetomidine attenuates brain ischemia reperfusion injury possibly via up-regulation of astrocyte Connexin 43
por: Zheng, Xiaoyang, et al.
Publicado: (2020)

Exosomes From Astrocyte Processes: Signaling to Neurons
por: Venturini, Arianna, et al.
Publicado: (2019)

Modified heptapeptide from tau binds both tubulin and microtubules
por: Li, Jingrui, et al.
Publicado: (2020)

Anticancer Activities of Newly Synthesized Chiral Macrocyclic Heptapeptide Candidates
por: Abo-Ghalia, Mohamed H., et al.
Publicado: (2020)

Shaping of Hepatic Ischemia/Reperfusion Events: The Crucial Role of Mitochondria
por: Teodoro, João S., et al.
Publicado: (2022)

Ischemia-Reperfusion under Hyperthermia Increases Heme Oxygenase-1 in Pyramidal Neurons and Astrocytes with Accelerating Neuronal Loss in Gerbil Hippocampus
por: Lee, Tae-Kyeong, et al.
Publicado: (2021)

Effect of sevoflurane preconditioning on astrocytic dynamics and neural network formation after cerebral ischemia and reperfusion in rats
por: Yu, Qiong, et al.
Publicado: (2019)

Plasma exosomes induced by remote ischaemic preconditioning attenuate myocardial ischaemia/reperfusion injury by transferring miR-24
por: Minghua, Wen, et al.
Publicado: (2018)

Somatosensory Cortical Electrical Stimulation After Reperfusion Attenuates Ischemia/Reperfusion Injury of Rat Brain
por: Wang, Liang-Chao, et al.
Publicado: (2021)

Melatonin Attenuates Cardiac Ischemia-Reperfusion Injury through Modulation of IP3R-Mediated Mitochondria-ER Contact
por: Li, Wenya, et al.
Publicado: (2021)

A Novel Heptapeptide, GPPGPAG Transfers to the Brain, and Ameliorates Memory Dysfunction and Dendritic Atrophy in Alzheimer’s Disease Model Mice
por: Tohda, Chihiro, et al.
Publicado: (2021)

Panax notoginseng: derived exosome-like nanoparticles attenuate ischemia reperfusion injury via altering microglia polarization
por: Li, Shiyi, et al.
Publicado: (2023)

Roles of Nitric Oxide in Brain Ischemia and Reperfusion
por: Wang, Yijie, et al.
Publicado: (2022)

Effects of a Particular Heptapeptide on the IFN-α-Sensitive CML Cells
por: Yang, Fu-lan, et al.
Publicado: (2015)

Identification and Characterization of Novel Fc-Binding Heptapeptides from Experiments and Simulations
por: Sun, Xiaoquan, et al.
Publicado: (2018)

Curcumin attenuates myocardial ischemia–reperfusion injury
por: Liu, Kun, et al.
Publicado: (2017)

Effects of Lycopene Attenuating Injuries in Ischemia and Reperfusion
por: Wu, Sijia, et al.
Publicado: (2022)

Mitochondria-Targeted Antioxidants: Future Perspectives in Kidney Ischemia Reperfusion Injury
por: Kezic, Aleksandra, et al.
Publicado: (2016)

Mitochondria as a therapeutic target for cardiac ischemia-reperfusion injury (Review)
por: Marin, Wenwen, et al.
Publicado: (2021)

Calpain-mediated protein targets in cardiac mitochondria following ischemia–reperfusion
por: Li, Ling, et al.
Publicado: (2022)

Critical hubs of renal ischemia-reperfusion injury: endoplasmic reticulum-mitochondria tethering complexes
por: Zhao, Huan-Huan, et al.
Publicado: (2020)

Plasma Exosomes at the Late Phase of Remote Ischemic Pre-conditioning Attenuate Myocardial Ischemia-Reperfusion Injury Through Transferring miR-126a-3p
por: Li, Danni, et al.
Publicado: (2021)

Suppression of Excessive Histone Deacetylases Activity in Diabetic Hearts Attenuates Myocardial Ischemia/Reperfusion Injury via Mitochondria Apoptosis Pathway
por: Wu, Yang, et al.
Publicado: (2017)

Retracted: Melatonin Attenuates Cardiac Ischemia-Reperfusion Injury through Modulation of IP3R-Mediated Mitochondria-ER Contact
por: Longevity, Oxidative Medicine and Cellular
Publicado: (2023)

Effect of DJ-1 on the neuroprotection of astrocytes subjected to cerebral ischemia/reperfusion injury
por: Peng, Li, et al.
Publicado: (2018)

MiR-375 attenuates injury of cerebral ischemia/reperfusion via targetting Ctgf
por: Ou, Jianying, et al.
Publicado: (2017)

Liraglutide preconditioning attenuates myocardial ischemia/ reperfusion injury via homer1 activation
por: Cui, Xiangrong, et al.
Publicado: (2021)

Effect of TMAO and Urea on Dimers and Tetramers of Amyloidogenic Heptapeptides ((23)FGAILSS(29))
por: Khan, Ashma, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_37b12b5dg6ggoe4vpou5aagu2i