Excessive mechanical stress-induced intervertebral disc degeneration is related to Piezo1 overexpression triggering the imbalance of autophagy/apoptosis in human nucleus pulpous

BACKGROUND: Mechanical stress plays a crucial role in the pathogenesis of intervertebral disc degeneration (IVDD). The mechanosensitive Piezo1 ion channel can sense the changes in mechanical stress and convert the mechanical signals into chemical signals. This study aims to investigate the effect of...

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Detalles Bibliográficos
Autores principales: Shi, Sheng, Kang, Xing-Jian, Zhou, Zhi, He, Zhi-Min, Zheng, Shuang, He, Shi-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125856/
https://www.ncbi.nlm.nih.gov/pubmed/35606793
http://dx.doi.org/10.1186/s13075-022-02804-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125856/
https://www.ncbi.nlm.nih.gov/pubmed/35606793
http://dx.doi.org/10.1186/s13075-022-02804-y

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