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CCR5 activation and endocytosis in circulating tumor-derived cells isolated from the blood of breast cancer patients provide information about clinical outcome

BACKGROUND: CCR5 is a motility chemokine receptor implicated in tumor progression, whose activation and subsequent endocytosis may identify highly aggressive breast cancer cell subtypes likely to spread into the circulatory system. METHODS: The MDA-MB-231 cell line was used to model and visualize CC...

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Detalles Bibliográficos
Autores principales: Raghavakaimal, Ashvathi, Cristofanilli, Massimo, Tang, Cha-Mei, Alpaugh, R. K., Gardner, Kirby P., Chumsri, Saranya, Adams, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125938/
https://www.ncbi.nlm.nih.gov/pubmed/35606863
http://dx.doi.org/10.1186/s13058-022-01528-w