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Analysis of hemisphere-dependent effects of unilateral intrastriatal injection of α-synuclein pre-formed fibrils on mitochondrial protein levels, dynamics, and function

Genetic and neuropathological evidence strongly implicates aberrant forms of α-synuclein in neurodegeneration. Antibodies specific for α-synuclein phosphorylated at serine 129 (pS129) are selective for the pathological protein aggregates that are characteristic of Parkinson’s disease (PD) and other...

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Detalles Bibliográficos
Autores principales: Creed, Rose B., Memon, Adeel A., Komaragiri, Sindhu P., Barodia, Sandeep K., Goldberg, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125944/
https://www.ncbi.nlm.nih.gov/pubmed/35606853
http://dx.doi.org/10.1186/s40478-022-01374-z