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COH04S1 and beta sequence-modified vaccine protect hamsters from SARS-CoV-2 variants

COVID-19 vaccine efficacy is threatened by emerging SARS-CoV-2 variants of concern (VOC) with the capacity to evade protective neutralizing antibody responses. We recently developed clinical vaccine candidate COH04S1, a synthetic modified vaccinia Ankara vector (sMVA) co-expressing spike and nucleoc...

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Detalles Bibliográficos
Autores principales: Wussow, Felix, Kha, Mindy, Faircloth, Katelyn, Nguyen, Vu H., Iniguez, Angelina, Martinez, Joy, Park, Yoonsuh, Nguyen, Jenny, Kar, Swagata, Andersen, Hanne, Lewis, Mark G., Chiuppesi, Flavia, Diamond, Don J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126022/
https://www.ncbi.nlm.nih.gov/pubmed/35634578
http://dx.doi.org/10.1016/j.isci.2022.104457