Lack of STAT6 enhances murine acute lung injury through NLRP3/p38 MAPK signaling pathway in macrophages

BACKGROUND: Signal transducer and activator of transcription 6 (STAT6) is an intracelluar transcriotion factor and NLRP3 (Nod-like receptor containing a pyrin domain 3) is a component of NLRP3 inflammasome in pyroptotic cells. There was increased activation of STAT6 and expression of NLRP3 in mice w...

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Detalles Bibliográficos
Autores principales: Hu, Lu, Shao, Changzhou, Pan, Linyue, Jiang, Zhilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126100/
https://www.ncbi.nlm.nih.gov/pubmed/35606692
http://dx.doi.org/10.1186/s12865-022-00500-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126100/
https://www.ncbi.nlm.nih.gov/pubmed/35606692
http://dx.doi.org/10.1186/s12865-022-00500-9

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