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Leucine-Rich Repeats and Transmembrane Domain 2 Controls Protein Sorting in the Striatal Projection System and Its Deficiency Causes Disturbances in Motor Responses and Monoamine Dynamics

The striatum is involved in action selection, and its disturbance can cause movement disorders. Here, we show that leucine-rich repeats and transmembrane domain 2 (Lrtm2) controls protein sorting in striatal projection systems, and its deficiency causes disturbances in monoamine dynamics and behavio...

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Detalles Bibliográficos
Autores principales: Ichise, Misato, Sakoori, Kazuto, Katayama, Kei-ichi, Morimura, Naoko, Yamada, Kazuyuki, Ozawa, Hiroki, Matsunaga, Hayato, Hatayama, Minoru, Aruga, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126195/
https://www.ncbi.nlm.nih.gov/pubmed/35615067
http://dx.doi.org/10.3389/fnmol.2022.856315