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Leucine-Rich Repeats and Transmembrane Domain 2 Controls Protein Sorting in the Striatal Projection System and Its Deficiency Causes Disturbances in Motor Responses and Monoamine Dynamics
The striatum is involved in action selection, and its disturbance can cause movement disorders. Here, we show that leucine-rich repeats and transmembrane domain 2 (Lrtm2) controls protein sorting in striatal projection systems, and its deficiency causes disturbances in monoamine dynamics and behavio...
Autores principales: | Ichise, Misato, Sakoori, Kazuto, Katayama, Kei-ichi, Morimura, Naoko, Yamada, Kazuyuki, Ozawa, Hiroki, Matsunaga, Hayato, Hatayama, Minoru, Aruga, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126195/ https://www.ncbi.nlm.nih.gov/pubmed/35615067 http://dx.doi.org/10.3389/fnmol.2022.856315 |
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