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Liver regeneration and ethanol detoxification: A new link in YAP regulation of ALDH1A1 during alcohol‐related hepatocyte damage

Yes‐associated protein (YAP), a central effector in the Hippo pathway, is involved in the regulation of organ size, stem cell self‐renewal, and tissue regeneration. In this study, we observed YAP activation in patients with alcoholic steatosis, hepatitis, and cirrhosis. Accumulation of this protein...

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Detalles Bibliográficos
Autores principales: Zhou, Junmei, Sun, Chunbao, Yang, Lu, Wang, Jinhui, Jn‐Simon, Natacha, Zhou, Chen, Bryant, Andrew, Cao, Qi, Li, Chenglong, Petersen, Bryon, Pi, Liya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126254/
https://www.ncbi.nlm.nih.gov/pubmed/35218575
http://dx.doi.org/10.1096/fj.202101686R