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Deciphering the Link Between ER(UPR) Signaling and MicroRNA in Pathogenesis of Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative proteinopathic disease. The deposits of misfolded Amyloid β and Tau proteins in the brain of patients with AD suggest an imbalance in endoplasmic reticulum (ER) proteostasis. ER stress is due to accumulation of aberrant proteins in the ER lumen, which...

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Detalles Bibliográficos
Autores principales: Yasmeen, Nusrath, Datta, Manali, Kumar, Vikram, Alshehri, Fahad S., Almalki, Atiah H., Haque, Shafiul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126300/
https://www.ncbi.nlm.nih.gov/pubmed/35615589
http://dx.doi.org/10.3389/fnagi.2022.880167