Cargando…
Deciphering the Link Between ER(UPR) Signaling and MicroRNA in Pathogenesis of Alzheimer’s Disease
Alzheimer’s disease (AD) is a neurodegenerative proteinopathic disease. The deposits of misfolded Amyloid β and Tau proteins in the brain of patients with AD suggest an imbalance in endoplasmic reticulum (ER) proteostasis. ER stress is due to accumulation of aberrant proteins in the ER lumen, which...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126300/ https://www.ncbi.nlm.nih.gov/pubmed/35615589 http://dx.doi.org/10.3389/fnagi.2022.880167 |