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APE1 shRNA‐loaded cancer stem cell‐derived extracellular vesicles reverse Erlotinib resistance in non‐small cell lung cancer via the IL‐6/STAT3 signalling

OBJECTIVE: Apurinic endonuclease 1 (APE1) has been suggested as an oncogene of lung tumours and our bioinformatics analysis identified the association between Erlotinib resistance and interleukin‐6 (IL‐6). Thus, we performed this work to delineate the mechanistic actions of APE1/IL‐6 signalling in E...

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Detalles Bibliográficos
Autores principales: Tang, Chun‐Han, Qin, Ling, Gao, Ying‐Chun, Chen, Tai‐Yu, Xu, Ke, Liu, Tao, Ren, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9126360/
https://www.ncbi.nlm.nih.gov/pubmed/35605028
http://dx.doi.org/10.1002/ctm2.876